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Exhale-Dx™ is a non-invasive point of care device, that implements breath analysis to forecast your future diagnosis. This provides the patient with personalised self-management.

Breath Analysis

Applied Nanodetectors (AND) is commercialising point of care exhaled breath diagnostics to identify and manage chronic diseases to give fast and reliable information to improve patient outcomes and help healthcare experts make the right decisions. We have developed a new rapid non-invasive handheld breath test system using AND’s patented nanotechnology-based gas sensors that can detect biomarkers in the breath for diagnosis and management of chronic conditions. This technology will be used by people suffering from chronic conditions at several points in the healthcare supply chain (at home, in the general practitioner’s office or the hospital environment) to more efficiently manage their chronic condition, reduce hospital costs and improve their quality of life. Breath analysis is a non-invasive test whereby small quantities of volatile organic compounds (VOCs) can be detected in human breath, and they can form a fingerprint that can be used for early disease detection and diagnosis.

End-Tidal Breath Collection

One of the main technical challenges is that there are no standardized methods for the collection of VOC breath samples. Concentrations of volatile compounds in the blood are reflected by their concentrations in the exhaled air and alveolar breath is the part of exhaled air in equilibrium with systemic blood, whereas end-tidal air is the last fraction of expired air, whose composition resembles alveolar air. We have developed an end-tidal collection method to collect breath samples from a specific breath fraction. Our breath collection algorithms enable breath samples to be measured in a reliable way to ensure repeatable and reproducible measurements.

Mobile Application for Supported Self-Care

Effective disease management requires information about the patient’s history and medications, which is also accessible by their healthcare practitioners. A self-care mobile application needs to be easily used by the patient and facilitates data sharing safely and reliably. Our mobile application platform includes information about their medication, alerts/reminders and their action plan. The mobile application can be personalised to offer supported self-management service. Also, our new mobile application uses an interactive method to facilitate user engagement and help with drug adherence.

Yasmine Al-Shaghay

Author Yasmine Al-Shaghay

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